MIT scientists have published a model designed to help predict which kinase pathways may be inhibited by kinase inhibitors
Filed under: kinase | Tagged: kinase, Research | Leave a Comment »
Nervianos Cdc7 inhibitor PHA-767491 causes apoptosis in multiple cell lines
Posted on May 20, 2008 by crimsoncanary
Nerviano Medical Sciences report that its Cdc7 inhibitor PHA-767491 causes apoptosis and cell death in a variety of cancer cell types and inhibits tumor growth in preclinical cancer models.
Filed under: kinase | Tagged: cdc7, nerviano, PHA-767491, PHA767491 | Leave a Comment »
Iressa (gefitinib) shows promise in Breast cancer
Posted on May 20, 2008 by crimsoncanary
Researchers at the MD Anderson Cancer Center have shown that Gefitinib shows potential in the treatment of Breast cancer when administered in combination with Arimidex
Filed under: kinase | Tagged: AstraZeneca, EGF kinase, gefitinib, Iressa, kinase | Leave a Comment »
AstraZeneca and Cancer Research UK partner for AZD0424 development
Posted on May 20, 2008 by crimsoncanary
AstraZeneca and Cancer Research UK are collaborating on clinical development of AZD-0424, a Src/Abl kinase inhibitor
Filed under: kinase | Tagged: Abl, AstraZeneca, azd-0424, azd0424, kinase, SRC | Leave a Comment »
KAI advance KAI-1678, PKC inhibitor into Phase I
Posted on May 20, 2008 by crimsoncanary
Kai Pharmaceutical’s have advacned its PKC epsilon inhibitor KAI-1678 in to Phase I clinical trials. It has potential in the treatment of pain.
Filed under: kinase | Tagged: kai, KAI-1678, KAI1678, kinase, PKC, PKC epsilon, PKCepsilon | Leave a Comment »
