Methygene initiate second Phase I trial of c-Met inhibitor MGCD265 in Cancer

MethylGene have initiated a second phase I trial of its c-Met inhibitor MGCD-265 in patients with solid tumours

Tykerb receives conditional EU marketing approval for HER2 breast cancer

GlaxoSmithKline have received a conditional marketing authorisation from the european autorities for lapatinib (Tyverb, Tykerb). The approval is for the use of lapatinib in advanced or metastatic HER2 positive breast cancer in combination with capecitabine.

Rigels Syk inhibitor R788 enters Phase 2b trials in RA

Rigel have announced that its Syk inhibitor R788 has entered phase IIb clinical trials in Rheumatoid Arthritis (RA)