Pfizer have published data on PF-00299804, a second-generation irreversible pan-erbB receptor kinase inhibitor currently in phase I clinical trials.
Filed under: kinase | Tagged: erb, ErbB1, ErbB2, ErbB3, PF-00299804, Pfizer, Preclinical, Research | Comments Off
Novartis have published data on the identification and characterization of a new phosphatidylinositol 3-kinase (PI3K)/Akt/mTOR inhibitor NVP-BEZ235
Filed under: kinase | Tagged: akt, kinase, mTOR, Novartis, NVP-BEZ235, NVPBEZ235, PI3K, Preclinical, Research | Comments Off
Preclinical data presented at the European Society for Medical Oncology Conference show Hana Biosciences Menadione Topical Lotion is effective in the treatment and/or prevention of Epidermal Growth Factor Receptor Inhibitor (EGFRI) associated skin toxicities.
Filed under: kinase | Tagged: EGFR, Hana Biosciences, kinase, Menadione, Preclinical, Research | Comments Off
ImClone Systems have announced the start of a Phase II clinical trial of IMC-A12, its IGF-1R monoclonal antibody in adolescents and adult patients with several types of soft tissue sarcoma.
Filed under: Kinase receptor | Tagged: IGF-1R, IMC-A12, IMCA12, ImClone, MAb, Monoclonal, Phase II, Sarcoma | Comments Off
