AstraZeneca publish discovery of Imidazole piperazine CDK inhibitors

AstraZeneca have published the synthesis fo a series of imidazole piperazine cyclin-dependent kinase (CDK) inhibitors.

GSK disclose discovery of Pazopanib

GSK have published the sysnthesis of VEGF inhibitor Pazopanib under clinical development for renal-cell cancer and other solid tumors.