IGF-1R/FAK inhibitor TAE226 shows efficacy in preclinical studies

Posted on July 15, 2008 by crimsoncanary

Novartis’ FAK/IGF-1R inhibitor TAE226 has shown anti tumor activity in Barrett’s esophageal adenocarcinoma tissues

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Genentech halt Avastin/Sutent trial following cases of microangiopathic hemolytic anemia (MAHA)

Posted on July 15, 2008 by crimsoncanary

Genentech have halted its trial of Avastin in combination with Sutent following reports of several cases of microangiopathic hemolytic anemia (MAHA) in patients with solid tumors

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OSI begin Phase I with TORC1/2 inhibitor OSI-027

Posted on July 15, 2008 by crimsoncanary

OSI Pharmaceuticals have begun Phase I Clinical Development for OSI-027, the first orally available small molecule that inhibits both TORC1 and TORC2, in Patients with Advanced Solid Tumors or Lymphoma.

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