UCB publish series for PI3K inhibitors

UCB have published a series of phosphoinositide 3-kinase (PI3K) inhibitors for the treatment of cancer

Nexavar approved for hepatocellular carcinoma in China

Bayer and Onyx have announced that Nexavar has been approved for the treatment of patients with unresectable or metastatic hepatocellular carcinoma (HCC), or liver cancer in China

Astex publish series of CDK2 inhibitors

Astex have publised a series of CDK2 inhibitors with low affinity for the enzyme

Exelixis MET/RET/VEGFR2 inhibitor XL184 achieves proof of concept in cancer

Exelixis have announced that its MET/RET/VEGFR2 inhibitor XL184 has achieved proof of concept in hematologic cancers. The company has submitted data to its partner GSK who has 90 days to review the data and decide whether to exercise its option to select the compound for further development and commercialization.