PLK1 siRNA prevents growth of liver metastases

Researchers at Kyoto University have shown that siRNA directed against PLK1, when administered with atelocollagen as a drug delivery system prevents the growth of liver metastases in a murine liver metastasis model of lung cancer.

RAD001/Sandostatin combo shows efficacy in pancreatic cancer

Data presented at the European of Medical Oncology (ESMO) show that combining RAD001 with Sandostatin demonstrates clinical benefits in 82% of  pancreatic neurocrine cancer patients

CHK1 inhibitor AZD7762 potentiates antitimor activity in vivo and in vitro

AstraZeneca’s CHK1 inhibitor AZD7762 potentiates antitimor activity in vivo and in vitro when administered in combination with DNA-damaging agents