Cytopia to present JAK2 data at conferences

Cytopia Limited are to present data on its JAK2 inhibitor program at two important scientific meetings this month – the Hematological Society of Australia and New Zealand and the ‘Drug Discovery on Target’ conference in Boston USA

Supergen to present on Kinase drugs at EORTC-NCI-AACR

SuperGen are to present data on the following kinase inhibitors at the 20th EORTC-NCI-AACR Symposium
Abstract 403, 426: MP-470, multikinase inhibitor
Abstract 332: SGI-1776, PIM kinase inhibitor
Abstract 571: SGI-1252,  JAK2 kinase inhibitor

Incytes JAK2 inhibitor INCB18424 demonstrates POC in Psoriasis

Incyte have reported positive results from Phase IIa clinical trials of JAK2 inhibitor INCB18424 in patients with mild to moderate psoriasis.

S*BIO Initiate Phase I trial of JAK2 Inhibitor SB1518

S*BIO Pte have announced the initiation of multi-center Phase I clinical trials of JAK2 inhibitor SB1518 in patients with leukemia and certain types of lymphoma.

AstraZenecas JAK2 inhibitor AZ960 active in vitro

AstraZenecas AZ960 inhibits JAK2 with a Ki of 0.00045 µM in vitro and demostrates apoptic activity in cell based assays

S*Bio initate Phase I/II trial of JAK2 inhibitor SB1518 in Chronic Idiopathic Myelofibrosis

S*Bio have initated a Phase I/II trial of JAK2 inhibitor SB1518 in Chronic Idiopathic Myelofibrosis diseases including Myelofibrosis, Myeloproliferative Disorders, Polycythemia Vera and Essential Thrombocythemia

Cytopia to present on JAK2 program at ACS meeting

Cytopia have announced that it will be presenting data on its JAK2 program at the Philadelphia ACS meeting.

Incyte report on INCB18424 and INCB28050 progress

In 2nd quarter results Incyte have provided an update on JAK2 inhibitors INC18424 and INCB28050

Cytopia gearing up for JAK2 clinical trial

Cytopia have appointed a Study chair at the Mayo Clinic in preparation of Phase I JAK2 trials for myelofibrosis

SuperGens JAK2 inhibitor SGI-1252 inhibits tumor cell proliferation in vivo

Data presented at the European Hematology Association show SuperGen’s JAK2 inhibitor SGI-1252 to inhibitor tumor cell proliferation in mouse xenograft models.