Pfizer have published a series of PYK2 inhibitors

Pfizer have published a series of trifluoromethylpyrimidine proline-rich tyrosine kinase 2 (PYK2) inhibitors

Novartis publish series of MK2 inhibitors

Novartis have published a series of pyrrolo-pyrimidone MK2 Inhibitors

J&J indentify new JAK3 inhibitors

J&J have published a series of Janus kinase 3 (JAK3) inhibitors

Pfizer publish series of MEK inhibitors

Pfizer have publsihed a series of MEK (MAP ERK Kinase) inhibitors.

Vertex publish series of Syk kinase inhibitors

Vertex have published a series of 4-Thiazolyl-2-phenylaminopyrimidine Spleen Tyrosine Kinase (SYK) inhibitors

Scripps Inst publish series of Rho kinase II inhibitors

Researchers from the Scripps Inst have published a series of Rho kinase 2 inhibitors. One compound had an IC50 of ~3 nM in enzyme and cell based assays.

Benzoxoloazepinolone (CID755673) is a potent Protein kinase D inhibitor

Researchers at the Univerrsity of Pittsburgh have identified benzoxoloazepinolone (CID755673) as a potent Protein kinase D inhibitor

Vorinostat enhances MK-0457 activity in AML/CML

Vorinostat has been found to enhance the activity of Aurora kinase inhibitor MK-0457 (VX-680) on cultured human (HL-60, OCI-AML3, and K562) and primary acute myelogenous leukemia (AML) and chronic myelogenous leukemia (CML) cells

Sunesis publish modified SNS-032 analogs

Sunesis have published a series of modified SNS-032 analogs

Boehringer Ingelheim publish series of ITK inhibitors

Boehringer Ingelheim have published a series of 2-Aminobenzimidazole ITK inhibitors